Acro-Pectoro-Renal Field Defect: Recognizing the Clinical Pattern and Coordinating Renal Surveillance The acro-pectoro-renal field defect is a rare congenital association linking limb (acro) anomalies, pectoral muscle aplasia/hypoplasia, and ipsilateral or contralateral renal malformations. Understanding the syndrome’s pattern is essential for early renal evaluation and prevention of silent kidney disease. Clinical pattern and why it matters Patients present with combinations of limb anomalies (e.g., syndactyly, radial hypoplasia), aplasia or hypoplasia of the pectoralis major (sometimes raising the differential of Poland sequence), and renal anomalies ranging from agenesis and duplication to hydronephrosis and ureteropelvic junction obstruction. Importantly, renal involvement may be asymptomatic in early life but carry long-term risks for hypertension, infection, or chronic kidney disease if unrecognized. https://www.marketresearchfuture.com/reports/acro-pectoro-renal-field-defect-market-34576 Diagnostic evaluation and recommended screening Any child with congenital pectoral muscle aplasia or significant limb anomalies should receive prompt renal ultrasound to screen for structural abnormalities. If ultrasound identifies hydronephrosis, ectopia, or other anomalies, further urologic workup (VCUG, MAG3/renal scintigraphy, or MRI depending on findings) is indicated. Management principles Management is individualized: orthopaedic or reconstructive surgery may address functional limb issues; porcine or prosthetic rehabilitation can support chest wall defects when clinically needed; urologic surgery treats obstructive lesions and preserves renal function. Prognosis and follow-up Prognosis depends on renal involvement severity and the presence of other congenital anomalies. Those with unilateral, nonobstructive renal anomalies often do well with routine surveillance, whereas infants with significant obstruction or horseshoe kidney may require surgical correction and extended follow-up. Clinical takeaway When evaluating infants with limb or chest wall defects, proactively include renal imaging in the diagnostic pathway. Early multidisciplinary involvement (pediatrics, orthopaedics, urology, genetics) ensures timely interventions that preserve renal health and optimize functional outcomes.

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